Water-Soluble Graphene Covalently Functionalized by Biocompatible Poly-L-lysine

被引:577
作者
Shan, Changsheng [1 ,2 ]
Yang, Huafeng [1 ,2 ]
Han, Dongxue [1 ,2 ,3 ]
Zhang, Qixian [1 ,2 ]
Ivaska, Ari [3 ]
Niu, Li [1 ,2 ,3 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China
[2] Chinese Acad Sci, Grad Univ, Changchun 130022, Peoples R China
[3] Abo Akad Univ, Analyt Chem Lab, Proc Chem Ctr, FI-20500 Turku, Finland
关键词
WALLED CARBON NANOTUBES; GRAPHITE OXIDE; AQUEOUS DISPERSIONS; SHEETS; FILMS; NANOPLATELETS; NANOCOMPOSITES; NANOPARTICLES; REDUCTION; CELL;
D O I
10.1021/la903265p
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Graphene sheets functionalized covalently with biocompatible poly-L-lysine (PLL) were first synthesized in all alkaline solution. PLL-functionalized graphene is water-soluble and biocompatible, which makes it a novel material promising for biological applications. Graphene sheets played an important role as connectors to assemble these active amino groups Of Poly-L-lysine, which provided a very biocompatible. environment for further functionalization, such as attaching bioactive molecules. As an example, an amplified biosensor toward H2O2 based on linking peroxidase onto PLL-functionalized graphene was investigated.
引用
收藏
页码:12030 / 12033
页数:4
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