Tools to rapidly produce and screen biodegradable polymer and sol-gel-derived xerogel formulations

被引：35

作者：

Cho, EJ

Tao, ZY

Tang, Y

Tehan, EC

Bright, FV

Hicks, WL

Gardella, JA

Hard, R

机构：

[1] SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA

[2] Roswell Pk Canc Inst, Dept Head & Neck Surg, Buffalo, NY 14263 USA

[3] SUNY Buffalo, Dept Anat & Cell Biol, Buffalo, NY 14214 USA

来源：

APPLIED SPECTROSCOPY | 2002年 / 56卷 / 11期

关键词：

rapid screening; protein-doped xerogels; biodegradable polymers; keratinocyte growth factor; monoclonal antifluorescein antibodies; protein activity;

D O I：

10.1366/00037020260377661

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

A new method to rapidly produce and screen biodegradable polymer- and xerogel-based formulations is described. The approach is based on a high-speed pin printer and imaging with an epi-fluorescence microscope/charge-coupled device detector. By using this approach we can produce and screen over 600 formulations/h and rapidly identify lead formulations and/or compositions that are the most useful for the development of biodegradable devices or (bio)sensors.

引用

页码：1385 / 1389

页数：5

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