A brief assessment of concerns associated with genetic testing for cancer: The Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire

被引：232

作者：

Cella, D

Hughes, C

Peterman, A

Chang, CH

Peshkin, BN

Schwartz, MD

Wenzel, L

Lemke, A

Marcus, AC

Lerman, C

机构：

[1] Evanston NW Healthcare, Ctr Outcomes Res & Educ, Evanston, IL 60201 USA

[2] Northwestern Univ, Inst Hlth Serv Res & Policy Studies, Evanston, IL 60208 USA

[3] Georgetown Univ, Lombardi Canc Ctr, Washington, DC 20057 USA

[4] Georgetown Univ, Dept Oncol, Washington, DC 20057 USA

[5] Univ Calif Irvine, Div Epidemiol, Irvine, CA 92717 USA

[6] AMC, Ctr Canc Res, Ctr Behav Res & Community Studies, Denver, CO USA

来源：

HEALTH PSYCHOLOGY | 2002年 / 21卷 / 06期

关键词：

cancer genetics; genetic testing; cancer risk assessment;

D O I：

10.1037//0278-6133.21.6.564

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

The Multidimensional Impact of Cancer Risk Assessment (MICRA) is a new tool to measure the specific impact of result disclosure after genetic testing. The authors compared its performance with that of questionnaires measuring general and cancer-specific distress. Participants (158 women) responded 1 month after they received genetic test results. The women were divided into 4 standard clinical test result groups: BRCA1/2 positive, BRCA1/2 negative, panel negative, and true negative. Factor analysis supported the formation of 3 subscales: Distress (6 items, alpha = .86), Uncertainty (9 items, alpha = .77), and Positive Experiences (4 items, alpha = .75). All 3 MICRA subscales differentiated participants who were BRCA1/2 positive from the other 3 groups. MICRA thus helps identify subgroups of vulnerable genetic testing participants.

引用

页码：564 / 572

页数：9

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