One-pot synthesis of new chiral sulfides and selenides containing oxazolidines: Catalyst in the enantioselective addition of diethylzinc to benzaldehyde

被引：40

作者：

Braga, AL ^{[1
]}

Rodrigues, OED

Paixao, MW

Appelt, HR

Silveira, CC

Bottega, DP

机构：

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

[2] Ctr Univ Franciscano, BR-97010032 Santa Maria, RS, Brazil

来源：

SYNTHESIS-STUTTGART | 2002年 / 16期

关键词：

sulfur; selenium; stereoselective synthesis; asymmetric catalysis; zinc;

D O I：

10.1055/s-2002-35225

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new easily accessible class of chiral sulfides 1 and selenides 2 containing oxazolidine was prepared from amino acids. They were used as chiral ligands in the catalytic asymmetric addition of diethylzinc to benzaldehyde to give the corresponding secondary alcohols in up to 80% ee with an R-configuration.

引用

页码：2338 / 2340

页数：3

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