Unsymmetrical diaryl sulfones through palladium-catalyzed coupling of aryl iodides and arenesulfinates

被引:121
作者
Cacchi, S [1 ]
Fabrizi, G [1 ]
Goggiamani, A [1 ]
Parisi, LM [1 ]
机构
[1] Univ Roma La Sapienza, Dipartimento Studi Chim & Tecnol Sostanze Biol At, I-00185 Rome, Italy
关键词
D O I
10.1021/ol0271887
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] The palladium-catalyzed coupling of aryl iodides and arenesulfinates provides a simple and extremely efficient new route to unsymmetrical diaryl sulfones, usually isolated in high yield. The reaction tolerates a variety of functionalized aryl iodides, including those containing ether, ester, and nitro groups. The best results have been obtained by using Pd-2(dba)(3), Xantphos, Cs2CO3, and (Bu4NCl)-Bu-n in toluene at 80degreesC.
引用
收藏
页码:4719 / 4721
页数:3
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