Unsymmetrical diaryl sulfones through palladium-catalyzed coupling of aryl iodides and arenesulfinates

被引：121

作者：

Cacchi, S ^{[1
]}

Fabrizi, G ^{[1
]}

Goggiamani, A ^{[1
]}

Parisi, LM ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dipartimento Studi Chim & Tecnol Sostanze Biol At, I-00185 Rome, Italy

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 26期

关键词：

D O I：

10.1021/ol0271887

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The palladium-catalyzed coupling of aryl iodides and arenesulfinates provides a simple and extremely efficient new route to unsymmetrical diaryl sulfones, usually isolated in high yield. The reaction tolerates a variety of functionalized aryl iodides, including those containing ether, ester, and nitro groups. The best results have been obtained by using Pd-2(dba)(3), Xantphos, Cs2CO3, and (Bu4NCl)-Bu-n in toluene at 80degreesC.

引用

页码：4719 / 4721

页数：3