A direct entry to carbasugars:: Asymmetric synthesis of 1-epi-(+)-MK7607

被引：32

作者：

Grondal, Christoph ^{[1
]}

Enders, Dieter ^{[1
]}

机构：

[1] Univ Aachen, Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

来源：

SYNLETT | 2006年 / 20期

关键词：

carbasugars; organocatalysis; asymmetric synthesis; aldol reaction; ring-closing metathesis;

D O I：

10.1055/s-2006-956495

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short and flexible synthesis of 5a-carbasugars is presented. The combination of a proline-catalyzed aldol reaction and a ring-closing metathesis affords 1-epi-(+)-MK7607 in seven steps with an overall yield of 23%.

引用

页码：3507 / 3509

页数：3

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