A mouse for all reasons

被引：311

作者：

Collins, Francis S.

机构：

[1] Univ Toronto, Hosp Sick Children, Toronto, ON M5G 1X8, Canada

[2] Tech Univ Munich, GSF, Natl Res Ctr Environm & Hlth, D-8000 Munich, Germany

来源：

CELL | 2007年 / 128卷 / 01期

关键词：

D O I：

10.1016/j.cell.2006.12.018

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three major mouse knockout programs are underway worldwide, working together to mutate all protein-encoding genes in the mouse using a combination of gene trapping and gene targeting in mouse embryonic stem (ES) cells. Although the current emphasis is on production of this valuable resource, there are significant efforts to facilitate program coordination, to enhance the availability of this resource, and to plan for future efforts in mouse genetics research.

引用

页码：9 / 13

页数：5

共 9 条

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