Antioxidative phenolics from the fresh leaves of Ternstroemia japonica

被引:18
作者
Jo, Youngmi [1 ]
Kim, Minkyung [1 ]
Shin, Myung Hee [1 ]
Chung, Hae Young [1 ]
Jung, Jee H. [1 ]
Im, Kwang Sik [1 ]
机构
[1] Pusan Natl Univ, Coll Pharm, Pusan 609735, South Korea
来源
JOURNAL OF NATURAL PRODUCTS | 2006年 / 69卷 / 10期
关键词
D O I
10.1021/np060096w
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Six new phenylethanoid glucosides, ternstrosides A-F (1-6), a new kaempferol derivative ( 7), and eight known compounds were isolated from the fresh leaves of Ternstroemia japonica. The structures were elucidated by 1D and 2D NMR spectroscopic analyses. Compounds 1-7 showed potent antioxidative activity in three different tests, with IC50 values in the range 3.26-6.50 mu M in the hydroxyl radical((OH)-O-center dot) inhibitory activity test, 33.29-82.21 mu M in the total ROS ( reactive oxygen species) inhibitory activity test, and 1.14-13.53 mu M in the peroxynitrite (ONOO-) scavenging activity test.
引用
收藏
页码:1399 / 1403
页数:5
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