Antioxidative phenolics from the fresh leaves of Ternstroemia japonica

被引：18

作者：

Jo, Youngmi ^{[1
]}

Kim, Minkyung ^{[1
]}

Shin, Myung Hee ^{[1
]}

Chung, Hae Young ^{[1
]}

Jung, Jee H. ^{[1
]}

Im, Kwang Sik ^{[1
]}

机构：

[1] Pusan Natl Univ, Coll Pharm, Pusan 609735, South Korea

来源：

JOURNAL OF NATURAL PRODUCTS | 2006年 / 69卷 / 10期

关键词：

D O I：

10.1021/np060096w

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Six new phenylethanoid glucosides, ternstrosides A-F (1-6), a new kaempferol derivative ( 7), and eight known compounds were isolated from the fresh leaves of Ternstroemia japonica. The structures were elucidated by 1D and 2D NMR spectroscopic analyses. Compounds 1-7 showed potent antioxidative activity in three different tests, with IC50 values in the range 3.26-6.50 mu M in the hydroxyl radical((OH)-O-center dot) inhibitory activity test, 33.29-82.21 mu M in the total ROS ( reactive oxygen species) inhibitory activity test, and 1.14-13.53 mu M in the peroxynitrite (ONOO-) scavenging activity test.

引用

页码：1399 / 1403

页数：5

共 24 条

[21] Triterpenoid saponins from the fruits of Ternstroemia japonica [J].

Shin, MH ;

Wang, WH ;

Nam, KI ;

Jo, Y ;

Jung, JH ;

Im, KS .

JOURNAL OF NATURAL PRODUCTS, 2003, 66 (10) :1351-1355

[22] Antioxidative phenylethanoid and phenolic glycosides from Picrorhiza scrophulariiflora [J].

Wang, H ;

Sun, Y ;

Ye, WC ;

Xiong, F ;

Wu, HJ ;

Yang, CH ;

Zhao, SX .

CHEMICAL & PHARMACEUTICAL BULLETIN, 2004, 52 (05) :615-617

[23] A FLAVONOL GLYCOSIDE FROM LYSIMACHIA-MAURITIANA [J].

YASUKAWA, K ;

TAKIDO, M .

PHYTOCHEMISTRY, 1987, 26 (04) :1224-1226

[24]

YOSIOKA I, 1972, CHEM PHARM BULL, V20, P1237

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