Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: A case-control study

被引：90

作者：

Bower, J. H.

Maraganore, D. M.

Peterson, B. J.

Ahlskog, J. E.

Rocca, W. A.

机构：

[1] Mayo Clin, Dept Neurol, Coll Med, Rochester, MN 55905 USA

[2] Mayo Clin, Div Biostat, Coll Med, Dept Hlth Sci Res, Rochester, MN 55905 USA

[3] Mayo Clin, Div Epidemiol, Coll Med, Dept Hlth Sci Res, Rochester, MN 55905 USA

来源：

NEUROLOGY | 2006年 / 67卷 / 03期

关键词：

D O I：

10.1212/01.wnl.0000227906.99570.cc

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors studied the association of markers of inflammation with the later development of Parkinson disease ( PD) using a case-control design ( 196 cases and 196 matched controls). The frequency of diseases of immediate-type hypersensitivity was significantly higher in cases than controls. In addition, cases used anti-inflammatory agents less frequently than controls ( nonsignificant trend). The results may support the hypothesis that there is an inflammatory component in the pathogenesis of PD.

引用

页码：494 / 496

页数：3

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