Structure and mechanism of iron-only hydrogenases

被引：186

作者：

Peters, JW ^{[1
]}

机构：

[1] Utah State Univ, Dept Chem & Biochem, Logan, UT 84322 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1999年 / 9卷 / 06期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0959-440X(99)00028-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The recent elucidation of the structures of iron-only hydrogenases from the microorganisms Clostridium pasteurianum and Desulfovibrio desulfuricans has revealed that the presumed site of reversible hydrogen oxidation exists as a unique, protein-associated organometallic prosthetic group. Details of the hydrogenase structures provide insight into the chemical mechanism of this highly evolved catalyst.

引用

页码：670 / 676

页数：7

共 28 条

[1] ADAMS MWW, 1987, J BIOL CHEM, V262, P15054
[2] Biochemistry - Biological hydrogen production: Not so elementary
Adams, MWW
Stiefel, EI
[J]. SCIENCE, 1998, 282 (5395) : 1842 - 1843
[3] HYDROGENASE
ADAMS, MWW
MORTENSON, LE
CHEN, JS
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1980, 594 (2-3) : 105 - 176
[4] THE STRUCTURE AND MECHANISM OF IRON-HYDROGENASES
ADAMS, MWW
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1020 (02) : 115 - 145
[5] Heterologous biosynthesis and characterization of the [2Fe-2S]-containing N-terminal domain of Clostridium pasteurianum hydrogenase
Atta, M
Lafferty, ME
Johnson, MK
Gaillard, J
Meyer, J
[J]. BIOCHEMISTRY, 1998, 37 (45) : 15974 - 15980
[6] Bioinorganic chemistry - Hydrogenase sophistication
Cammack, R
[J]. NATURE, 1999, 397 (6716) : 214 - 215
[7] The crystal structure of a reduced [NiFeSe] hydrogenase provides an image of the activated catalytic center
Garcin, E
Vernede, X
Hatchikian, EC
Volbeda, A
Frey, M
Fontecilla-Camps, JC
[J]. STRUCTURE WITH FOLDING & DESIGN, 1999, 7 (05): : 557 - 566
[8] Molecular characterization and transcriptional analysis of the putative hydrogenase gene of Clostridium acetobutylicum ATCC 824
Gorwa, MF
Croux, C
Soucaille, P
[J]. JOURNAL OF BACTERIOLOGY, 1996, 178 (09) : 2668 - 2675
[9] Biological activation of hydrogen
Happe, RP
Roseboom, W
Pierik, AJ
Albracht, SPJ
Bagley, KA
[J]. NATURE, 1997, 385 (6612) : 126 - 126
[10] Removal of the bridging ligand atom at the Ni-Fe active site of [NiFe] hydrogenase upon reduction with H2, as revealed by X-ray structure analysis at 1.4 Å resolution
Higuchi, Y
Ogata, H
Miki, K
Yasuoka, N
Yagi, T
[J]. STRUCTURE WITH FOLDING & DESIGN, 1999, 7 (05): : 549 - 556

← 1 2 3 →