Palladium-tetraphosphine as catalyst precursor for high-turnover-number Negishi cross-coupling of alkyl- or phenylzinc derivatives with aryl bromides

被引：54

作者：

Kondolff, Isabelle ^{[1
]}

Doucet, Henri ^{[1
]}

Santelli, Maurice ^{[1
]}

机构：

[1] Fac Sci & Tech St Jerome, CNRS, Lab Synth Organ Assoc, F-13397 Marseille 20, France

来源：

ORGANOMETALLICS | 2006年 / 25卷 / 22期

关键词：

D O I：

10.1021/om060605p

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The system combining the tetraphosphine cis,cis,cis-1,2,3,4- tetrakis(diphenylphosphinomethyl)cyclopentane (Tedi-cyp) and [Pd(C3H5)Cl](2) has been found to be a very active catalyst for the cross-coupling of aryl bromides with alkyl- or arylzinc derivatives (Negishi reaction). A variety of aryl bromides react in good yields and high turnover numbers (TONs) (up to 800 000) with diethylzinc, n-butylzinc bromide, or n-hexylzinc bromide in the presence of 0.1-0.0001 mol % catalyst in most cases.

引用

页码：5219 / 5222

页数：4

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