Noncontact measurement of nerve displacement during action potential with a dual-beam low-coherence interferometer

被引：66

作者：

Fang-Yen, C ^{[1
]}

Chu, MC

Seung, HS

Dasari, RR

Feld, MS

机构：

[1] MIT, George R Harrison Spect Lab, Cambridge, MA 02139 USA

[2] MIT, Howard Hughes Med Inst, Cambridge, MA 02139 USA

[3] MIT, Dept Brain & Cognit Sci, Cambridge, MA 02139 USA

来源：

OPTICS LETTERS | 2004年 / 29卷 / 17期

关键词：

D O I：

10.1364/OL.29.002028

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We have used a novel phase-referenced heterodyne dual-beam low-coherence interferometer to perform what we believe are the first noncontact measurements of surface motion in a nerve bundle during the action potential. Nerve displacements of similar to5-nm amplitude and similar to10-ms duration are measured without signal averaging. This interferometer may find general application in measurement of small motion in cells and other weakly scattering samples. (C) 2004 Optical Society of America.

引用

页码：2028 / 2030

页数：3

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