学术探索
学术期刊
新闻热点
数据分析
智能评审

Recombinational repair and restart of damaged replication forks

被引：340
作者：
McGlynn, P [1 ]
Lloyd, RG [1 ]
机构：
[1] Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham NG7 2UH, England
来源：
NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2002年 / 3卷 / 11期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1038/nrm951
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Genome duplication necessarily involves the replication of imperfect DNA templates and, if left to their own devices, replication complexes regularly run into problems. The details of how cells overcome these replicative 'hiccups' are beginning to emerge, revealing a complex interplay between DNA replication, recombination and repair that ensures faithful passage of the genetic material from one generation to the next.
引用
收藏
页码：859 / 870
页数：12
相关论文
共 121 条
  • [1] SEMIDOMINANT SUPPRESSORS OF SRS2 HELICASE MUTATIONS OF SACCHAROMYCES-CEREVISIAE MAP IN THE RAD51 GENE, WHOSE SEQUENCE PREDICTS A PROTEIN WITH SIMILARITIES TO PROKARYOTIC RECA PROTEINS
    ABOUSSEKHRA, A
    CHANET, R
    ADJIRI, A
    FABRE, F
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1992, 12 (07) : 3224 - 3234
  • [2] Double-strand break repair: are Rad51/RecA-DNA joints barriers to DNA replication?
    Aguilera, A
    [J]. TRENDS IN GENETICS, 2001, 17 (06) : 318 - 321
  • [3] DNA repair protein Rad55 is a terminal substrate of the DNA damage checkpoints
    Bashkirov, VI
    King, JS
    Bashkirova, EV
    Schmuckli-Maurer, J
    Heyer, WD
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (12) : 4393 - 4404
  • [4] Telomere position effect in human cells
    Baur, JA
    Zou, Y
    Shay, JW
    Wright, WE
    [J]. SCIENCE, 2001, 292 (5524) : 2075 - 2077
  • [5] Lesions in DNA: hurdles for polymerases
    Baynton, K
    Fuchs, RPP
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 2000, 25 (02) : 74 - 79
  • [6] Binding specificity determines polarity of DNA unwinding by the Sgs1 protein of S-cerevisiae
    Bennett, RJ
    Keck, JL
    Wang, JC
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1999, 289 (02) : 235 - 248
  • [7] Replication fork collapse at replication terminator sequences
    Bidnenko, V
    Ehrlich, SD
    Michel, B
    [J]. EMBO JOURNAL, 2002, 21 (14) : 3898 - 3907
  • [8] Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1
    Boddy, MN
    Lopez-Girona, A
    Shanahan, P
    Interthal, H
    Heyer, WD
    Russell, P
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (23) : 8758 - 8766
  • [9] Mus81-Eme1 are essential components of a Holliday junction resolvase
    Boddy, MN
    Gaillard, PHL
    McDonald, WH
    Shanahan, P
    Yates, JR
    Russell, P
    [J]. CELL, 2001, 107 (04) : 537 - 548
  • [10] Substrate specificity of RusA resolvase reveals the DNA structures targeted by RuvAB and RecG in vivo
    Bolt, EL
    Lloyd, RG
    [J]. MOLECULAR CELL, 2002, 10 (01) : 187 - 198
12345678910