An optical coherence microscope with enhanced resolving power in thick tissue

被引：137

作者：

Schmitt, JM

Lee, SL

Yung, KM

机构：

[1] Dept. of Elec. and Electron. Eng., Hong Kong Univ. of Sci. and Technol., Kowloon, Clear Water Bay

来源：

OPTICS COMMUNICATIONS | 1997年 / 142卷 / 4-6期

关键词：

microscopy; tomography; interferometry; biomedical optics;

D O I：

10.1016/S0030-4018(97)00280-0

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A new configuration of an optical coherence microscope for high-resolution imaging of biological tissues and other scattering materials is described. The microscope employs multiple sources and detectors combined with high-numerical-aperture optics to suppress speckle fluctuations and enhance resolution. Results of experiments on living tissue and tissue phantoms are presented to demonstrate the design principles of the microscope and to compare its performance to that of a conventional optical coherence microscope. (C) 1997 Elsevier Science B.V.

引用

收藏

页码：203 / 207

页数：5

相关论文

共 14 条

[1] HIGH-RESOLUTION OPTICAL COHERENCE TOMOGRAPHIC IMAGING USING A MODE-LOCKED TI-AL2O3 LASER SOURCE [J].

BOUMA, B ;

TEARNEY, GJ ;

BOPPART, SA ;

HEE, MR ;

BREZINSKI, ME ;

FUJIMOTO, JG .

OPTICS LETTERS, 1995, 20 (13) :1486-1488

[2] SPECKLE IN ULTRASOUND B-MODE SCANS [J].

BURCKHARDT, CB .

IEEE TRANSACTIONS ON SONICS AND ULTRASONICS, 1978, 25 (01) :1-6

[3] COHERENT 1-MU-M LIDAR MEASUREMENTS OF ATMOSPHERIC-TURBULENCE-INDUCED SPATIAL DECORRELATION USING A MULTIELEMENT HETERODYNE DETECTOR ARRAY [J].

CHAN, KP ;

KILLINGER, DK .

APPLIED OPTICS, 1992, 31 (10) :1505-1510

[4]

CLIVAZ X, 1995, P SOC PHOTO-OPT INS, V2083, P338

[5] EYE-LENGTH MEASUREMENT BY INTERFEROMETRY WITH PARTIALLY COHERENT-LIGHT [J].

FERCHER, AF ;

MENGEDOHT, K ;

WERNER, W .

OPTICS LETTERS, 1988, 13 (03) :186-188

[6] OPTICAL BIOPSY AND IMAGING USING OPTICAL COHERENCE TOMOGRAPHY [J].

FUJIMOTO, JG ;

BREZINSKI, ME ;

TEARNEY, GJ ;

BOPPART, SA ;

BOUMA, B ;

HEE, MR ;

SOUTHERN, JF ;

SWANSON, EA .

NATURE MEDICINE, 1995, 1 (09) :970-972

[7] OPTICAL COHERENCE TOMOGRAPHY [J].

HUANG, D ;

SWANSON, EA ;

LIN, CP ;

SCHUMAN, JS ;

STINSON, WG ;

CHANG, W ;

HEE, MR ;

FLOTTE, T ;

GREGORY, K ;

PULIAFITO, CA ;

FUJIMOTO, JG .

SCIENCE, 1991, 254 (5035) :1178-1181

[8]

PULIAFITO CA, 1995, OPHTHALMOLOGY, V102, P217

[9] SYNTHESIZED SOURCE FOR WHITE-LIGHT SENSING SYSTEMS [J].

RAO, YJ ;

NING, YN ;

JACKSON, DA .

OPTICS LETTERS, 1993, 18 (06) :462-464

[10] OPTICAL-COHERENCE TOMOGRAPHY OF A DENSE TISSUE - STATISTICS OF ATTENUATION AND BACKSCATTERING [J].

SCHMITT, JM ;

KNUTTEL, A ;

YADLOWSKY, M ;

ECKHAUS, MA .

PHYSICS IN MEDICINE AND BIOLOGY, 1994, 39 (10) :1705-1720