Genomics for environmental microbiology

被引:29
作者
Deutschbauer, Adam M.
Chivian, Dylan
Arkin, Adam P.
机构
[1] Lawrence Berkeley Natl Lab, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Howard Hughes Med Inst, Berkeley, CA 94720 USA
[3] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA
关键词
D O I
10.1016/j.copbio.2006.04.003
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The utilization of natural microbial diversity in biotechnology is hindered by our inability to culture the vast majority of microorganisms and the observation that laboratory engineered bacteria rarely function in the wild. It is now clear that an understanding of the community structure, function and evolution of bacteria in their natural environments is required to meet the promise of microbial biotechnology. To meet these new challenges, microbiologists are applying the tools of genomics and related high-throughput technologies to both cultured microbes and environmental samples. This work will lead to new views on ecosystems and biological function together with the biotechnology enabled by this science.
引用
收藏
页码:229 / 235
页数:7
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[1]   The MicrobesOnline web site for comparative genomics [J].
Alm, EJ ;
Huang, KH ;
Price, MN ;
Koche, RP ;
Keller, K ;
Dubchak, IL ;
Arkin, AP .
GENOME RESEARCH, 2005, 15 (07) :1015-1022
[2]   Do orthologous gene phylogenies really support tree-thinking? [J].
Bapteste, E ;
Susko, E ;
Leigh, J ;
MacLeod, D ;
Charlebois, RL ;
Doolittle, WF .
BMC EVOLUTIONARY BIOLOGY, 2005, 5 (1)
[3]  
Cases I, 2005, INT MICROBIOL, V8, P213
[4]   Bacterial Genomes as new gene homes:: The genealogy of ORFans in E-coli [J].
Daubin, V ;
Ochman, H .
GENOME RESEARCH, 2004, 14 (06) :1036-1042
[5]   PHYLOGENETIC STAINS - RIBOSOMAL RNA-BASED PROBES FOR THE IDENTIFICATION OF SINGLE CELLS [J].
DELONG, EF ;
WICKHAM, GS ;
PACE, NR .
SCIENCE, 1989, 243 (4896) :1360-1363
[6]   Community genomics among stratified microbial assemblages in the ocean's interior [J].
DeLong, EF ;
Preston, CM ;
Mincer, T ;
Rich, V ;
Hallam, SJ ;
Frigaard, NU ;
Martinez, A ;
Sullivan, MB ;
Edwards, R ;
Brito, BR ;
Chisholm, SW ;
Karl, DM .
SCIENCE, 2006, 311 (5760) :496-503
[7]   Monitoring gene expression in mixed microbial communities by using DNA microarrays [J].
Dennis, P ;
Edwards, EA ;
Liss, SN ;
Fulthorpe, R .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2003, 69 (02) :769-778
[8]   Rapid quantification and taxonomic classification of environmental DNA from both prokaryotic and eukaryotic origins using a microarray [J].
DeSantis, TZ ;
Stone, CE ;
Murray, SR ;
Moberg, JP ;
Andersen, GL .
FEMS MICROBIOLOGY LETTERS, 2005, 245 (02) :271-278
[9]   Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome [J].
Dufresne, A ;
Salanoubat, M ;
Partensky, F ;
Artiguenave, F ;
Axmann, IM ;
Barbe, V ;
Duprat, S ;
Galperin, MY ;
Koonin, EV ;
Le Gall, F ;
Makarova, KS ;
Ostrowski, M ;
Oztas, S ;
Robert, C ;
Rogozin, IB ;
Scanlan, DJ ;
de Marsac, NT ;
Weissenbach, J ;
Wincker, P ;
Wolf, YI ;
Hess, WR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (17) :10020-10025
[10]   Viral metagenomics [J].
Edwards, RA ;
Rohwer, F .
NATURE REVIEWS MICROBIOLOGY, 2005, 3 (06) :504-510