The MicrobesOnline web site for comparative genomics

被引:154
作者
Alm, EJ
Huang, KH
Price, MN
Koche, RP
Keller, K
Dubchak, IL
Arkin, AP [1 ]
机构
[1] Lawrence Berkeley Lab, Phys Biosci Div, Berkeley, CA 94720 USA
[2] Lawrence Berkeley Lab, Genom Div, Berkeley, CA 94720 USA
[3] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA
[4] Howard Hughes Med Inst, Berkeley, CA 94720 USA
关键词
D O I
10.1101/gr.3844805
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
At present, hundreds of microbial genomes have been sequenced, and hundreds more are currently in the pipeline. The Virtual Institute for Microbial Stress and Survival has developed a publicly available Suite of Web-based comparative genomic tools (http://www.microbesonline.org) designed to facilitate multispecies comparison among prokaryotes. Highlights of the MicrobesOnline Web site include operon and regulon predictions, a multispecies genome browser, a multispecies Gene Ontology browser, a comparative KEGG metabolic pathway viewer, a Bioinformatics Workbench for in-depth sequence analysis, and Gene Carts that allow users to save genes of interest for further study while they browse. In addition, we provide an interface for genome annotation, which like all of the tools reported here, is freely available to the scientific community.
引用
收藏
页码:1015 / 1022
页数:8
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