Polymer-assisted Horner-Emmons olefination using PASSflow reactors: Pure products without purification

被引：29

作者：

Solodenko, W

Kunz, U

Jas, G

Kirschning, A

机构：

[1] Leibniz Univ Hannover, Inst Organ Chem, D-30167 Hannover, Germany

[2] Tech Univ Clausthal, Inst Chem Verfahrenstech, D-38678 Clausthal Zellerfeld, Germany

[3] CHELONA GmbH, D-14473 Potsdam, Germany

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2002年 / 12卷 / 14期

关键词：

D O I：

10.1016/S0960-894X(02)00265-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A PASSflow protocol for the 1-Horner-Emmons olefination of aldehydes using polymer-bound hydroxide ions in flow-through reactors is presented which allows preparation of alkenes in very high yield with minimal purification. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1833 / 1835

页数：3

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