Solid-phase oligosaccharide synthesis: Preparation of complex structures using a novel linker and different glycosylating agents

被引：106

作者：

Andrade, RB ^{[1
]}

Plante, OJ ^{[1
]}

Melean, LG ^{[1
]}

Seeberger, PH ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 11期

关键词：

D O I：

10.1021/ol991071+

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A beta-(1-->4) linked trisaccharide was prepared in 53% yield on a polymer support using glycosyl phosphates and released by cross-metathesis of a novel linker to reveal the anomeric n-pentenyl glycoside. Heptasaccharide 33 was prepared in 9% yield in 14 steps.

引用

页码：1811 / 1814

页数：4

共 54 条

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