Use of response biomarkers in milk for assessing exposure to environmental contaminants: The case for dioxin-like compounds

被引：14

作者：

Diehl-Jones, WL ^{[1
]}

Bols, NC ^{[1
]}

机构：

[1] Univ Waterloo, Dept Biol, Waterloo, ON N2L 3G1, Canada

来源：

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS | 2000年 / 3卷 / 02期

关键词：

D O I：

10.1080/109374000281104

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Screening for environmental contaminants in milk is generally conducted by chemical analysis, yet such an approach may be time-consuming and expensive, and is not indicative of the physiological consequences of such exposure. The focus of this review is to summarize those constituents of milk that may be altered by maternal exposure to one of the most biologically active environmental pollutants, 2,3,7,8-tetrachlorodibenzo-p-dioxin, and to develop the case for their use as biomarkers of response. Several chemical and/or cellular components of milk are potentially useful as biomarkers, and may be developed as convenient, biologically relevant indicators of maternal exposure to dioxinlike compounds.

引用

页码：79 / 107

页数：29

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