Non-culture-based diagnostics for opportunistic fungi

被引:60
作者
Mennink-Kersten, Monique A. S. H.
Verweij, Paul E.
机构
[1] Radboud Univ Nijmegen, Nijmegen Med Ctr, Dept Med Microbiol, NL-6500 HB Nijmegen, Netherlands
[2] Univ Nijmegen, Ctr Infect Dis, NL-6500 HB Nijmegen, Netherlands
关键词
D O I
10.1016/j.idc.2006.06.009
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The value of the diagnostic markers galactomannan and 1,3-beta-D-glucan for the diagnosis of opportunistic fungal infections is reviewed in this article. Both markers have undergone clinical evaluation, and increasing insight is emerging with respect to the causes of false-negative or false-positive reactivity. These data will help design protocols in which single or multiple markers are used to identify patients who require antifungal therapy.
引用
收藏
页码:711 / +
页数:18
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