We present the case of a 13-year-old boy with an episode of aborted sudden death, absence of structural heart disease, and a characteristic ECG pattern of right bundle branch block with persistent ST-segment elevation in the right precordial leads, in whom a monomorphic sustained ventricular tachycardia developed spontaneously after the administration of ajmaline. This effect may be related to an increased inhomogeneity of repolarization mediated by the drug and demonstrates the arrhythmogenic potential of Class I antiarrhythmic drugs in patients with Brugada syndrome.
机构:
Beth Israel Deaconess Med Ctr, Harvard Thorndike Electrophysiol Inst, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Harvard Thorndike Electrophysiol Inst, Boston, MA 02215 USA
Krishnan, S
;
Josephson, ME
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机构:
Beth Israel Deaconess Med Ctr, Harvard Thorndike Electrophysiol Inst, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Harvard Thorndike Electrophysiol Inst, Boston, MA 02215 USA
机构:
Beth Israel Deaconess Med Ctr, Harvard Thorndike Electrophysiol Inst, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Harvard Thorndike Electrophysiol Inst, Boston, MA 02215 USA
Krishnan, S
;
Josephson, ME
论文数: 0引用数: 0
h-index: 0
机构:
Beth Israel Deaconess Med Ctr, Harvard Thorndike Electrophysiol Inst, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Harvard Thorndike Electrophysiol Inst, Boston, MA 02215 USA