Does nutrition play a role in the prevention and management of sarcopenia?

被引：404

作者：

Robinson, S. M. ^{[1
,2
]}

Reginster, J. Y. ^{[3
]}

Rizzoli, R. ^{[4
]}

Shaw, S. C. ^{[1
]}

Kanis, J. A. ^{[5
,6
]}

Bautmans, I. ^{[7
]}

Bischoff-Ferrari, H. ^{[8
]}

Bruyere, O. ^{[3
]}

Cesari, M. ^{[9
,10
]}

Dawson-Hughes, B. ^{[11
]}

Fielding, R. A. ^{[12
]}

Kaufman, J. M. ^{[13
]}

Landi, F. ^{[14
]}

Malafarina, V. ^{[15
,16
]}

Rolland, Y. ^{[17
]}

van Loon, L. J. ^{[18
]}

Vellas, B. ^{[19
,20
]}

Visser, M. ^{[21
,22
]}

Cooper, C. ^{[1
,2
,23
]}

机构：

[1] Univ Southampton, Southampton Gen Hosp, MRC Lifecourse Epidemiol Unit, Southampton SO16 6YD, Hants, England

[2] Univ Hosp Southampton NHS Fdn Trust, NIHR Southampton Biomed Res Ctr, Southampton, Hants, England

[3] Univ Liege, Quartier Hop, Dept Publ Hlth Epidemiol & Hlth Econ, Liege, Belgium

[4] Geneva Univ Hosp & Fac Med, Div Bone Dis, Geneva 14, Switzerland

[5] Catholic Univ Australia, Inst Hlth & Aging, Melbourne, Vic, Australia

[6] Univ Sheffield, Med Sch, Sheffield, S Yorkshire, England

[7] Vrije Univ Brussel, Gerontol & Frailty Ageing Res Dept, Brussels, Belgium

[8] Univ Zurich, Dept Geriatr & Aging Res, Zurich, Switzerland

[9] Univ Hosp Toulouse, Gerontopole, Toulouse, France

[10] Univ Toulouse III Paul Sabatier, INSERM UMR1027, Toulouse, France

[11] Tufts Univ, Jean Mayer USDA Human Nutr Res Ctr Aging, Bone Metab Lab, Boston, MA 02111 USA

[12] Tufts Univ, Jean Mayer USDA Human Nutr Res Ctr Aging, Nutr Exercise Physiol & Sarcopenia Lab, Boston, MA 02111 USA

[13] Ghent Univ Hosp, Dept Endocrinol, Unit Osteoporosis & Metab Bone Dis, Ghent, Belgium

[14] Univ Cattolica Sacro Cuore, Dept Geriat Neurosci & Orthoped, Milan, Italy

[15] Univ Navarra, Sch Pharm & Nutr, Dept Nutr Food Sci & Physiol, Pamplona, Spain

[16] Complejo Hosp Navarra, Dept Geriatr, Pamplona, Spain

[17] Univ Toulouse 3, UMR INSERM 1027, CHU Toulouse, Gerontopole Toulouse,Inst Vieillissement, Toulouse, France

[18] Maastricht Univ, NUTRIM Sch Nutr Toxicol & Metab, Maastricht, Netherlands

[19] CHU Toulouse, Serv Med Interne, Gerontopole, 170 Ave Casselardit, F-31059 Toulouse, France

[20] Gerontol Clin, 170 Ave Casselardit, F-31059 Toulouse, France

[21] Vrije Univ, Dept Hlth Sci, Amsterdam, Netherlands

[22] Vrije Univ Amsterdam Med Ctr, Internal Med, Dept Nutr & Dietet, Amsterdam, Netherlands

[23] Univ Oxford, Natl Inst Hlth Res Musculoskeletal Biomed Res Uni, Oxford OX3 7LE, England

来源：

CLINICAL NUTRITION | 2018年 / 37卷 / 04期

关键词：

Sarcopenia; Muscle mass; Muscle strength; Physical performance; Nutrition; Supplementation; POLYUNSATURATED FATTY-ACIDS; VITAMIN-D-RECEPTOR; DIETARY-PROTEIN INTAKE; SKELETAL-MUSCLE MASS; DWELLING OLDER-ADULTS; LEAN TISSUE MASS; PHYSICAL FUNCTION; MEDITERRANEAN DIET; D SUPPLEMENTATION; BODY-COMPOSITION;

D O I：

10.1016/j.clnu.2017.08.016

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

There is a growing body of evidence that links nutrition to muscle mass, strength and function in older adults, suggesting that it has an important role to play both in the prevention and management of sarcopenia. This review summarises the discussions of a working group [ESCEO working group meeting 8th September 2016] that met to review current evidence and to consider its implications for preventive and treatment strategies. The review points to the importance of 'healthier' dietary patterns that are adequate in quality in older age, to ensure sufficient intakes of protein, vitamin D, antioxidant nutrients and long-chain polyunsaturated fatty acids. In particular, there is substantial evidence to support the roles of dietary protein and physical activity as key anabolic stimuli for muscle protein synthesis. However, much of the evidence is observational and from high-income countries. Further high-quality trials, particularly from more diverse populations, are needed to enable an understanding of dose and duration effects of individual nutrients on function, to elucidate mechanistic links, and to define optimal profiles and patterns of nutrient intake for older adults. (C) 2017 The Authors. Published by Elsevier Ltd.

引用

页码：1121 / 1132

页数：12

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