Proton long-range migration along protein monolayers and its consequences on membrane coupling

被引:40
作者
Gabriel, B [1 ]
Teissie, J [1 ]
机构
[1] CNRS,INST PHARMACOL & BIOL STRUCT,F-31062 TOULOUSE 4,FRANCE
关键词
D O I
10.1073/pnas.93.25.14521
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
It has been shown with lipid layers and more recently with purple membranes that protons have slow surface-to-bulk transfer, This results in long-range proton lateral conduction along membranes, We report here that such lateral transfer can take place along a pure protein film, It is strongly controlled by the packing, Subtle reorganizations of the protein-protein contact can be biological switches between interfacial and delocalized proton pathways between sources and sinks.
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页码:14521 / 14525
页数:5
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