Fluorescent "light-up" bioprobes based on tetraphenylethylene derivatives with aggregation-induced emission characteristics

被引:487
作者
Tong, Hui
Hong, Yuning
Dong, Yongqiang
Haeussler, Matthias
Lam, Jacky W. Y.
Li, Zhen
Guo, Zufeng
Guo, Zhihong
Tang, Ben Zhong
机构
[1] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China
[2] Zhejiang Univ, Dept Polymer Sci & Engn, Hangzhou 310027, Peoples R China
关键词
D O I
10.1039/b608425g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Aggregation in poor solvents and complexation with calf thymus DNA and bovine serum albumin turn "on'' the fluorescence of tetraphenylethylene derivatives, due to the restriction of intra-molecular rotations of the dyes in the aggregates and complexes.
引用
收藏
页码:3705 / 3707
页数:3
相关论文
共 46 条
[1]   Single molecule fluorescence spectroscopy at ambient temperature [J].
Ambrose, WP ;
Goodwin, PM ;
Jett, JH ;
Van Orden, A ;
Werner, JH ;
Keller, RA .
CHEMICAL REVIEWS, 1999, 99 (10) :2929-2956
[2]   Enhanced emission and its switching in fluorescent organic nanoparticles [J].
An, BK ;
Kwon, SK ;
Jung, SD ;
Park, SY .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (48) :14410-14415
[3]   Design and synthesis of a novel enediynyl pentapeptide with predominantly β-turn structural motif and its potential as a fluorescence-based chemosensor [J].
Basak, A ;
Bag, SS ;
Basak, A .
BIOORGANIC & MEDICINAL CHEMISTRY, 2005, 13 (12) :4096-4102
[4]   Relaxation dynamics and structural characterization of organic nanoparticles with enhanced emission [J].
Bhongale, CJ ;
Chang, CW ;
Lee, CS ;
Diau, EWG ;
Hsu, CS .
JOURNAL OF PHYSICAL CHEMISTRY B, 2005, 109 (28) :13472-13482
[5]  
Bu''nau G. v., 1970, RANG DALESPHARMACOLO, V74, P1294, DOI [10.1002/bbpc.19700741223, DOI 10.1002/BBPC.19700741223]
[6]   Silole nanocrystals as novel biolabels [J].
Chan, CPY ;
Haeussler, M ;
Tang, BZ ;
Dong, YQ ;
Sin, KK ;
Mak, WC ;
Trau, D ;
Seydack, M ;
Renneberg, R .
JOURNAL OF IMMUNOLOGICAL METHODS, 2004, 295 (1-2) :111-118
[7]   Highly efficient organic light-emitting diodes with a silole-based compound [J].
Chen, HY ;
Lam, WY ;
Luo, JD ;
Ho, YL ;
Tang, BZ ;
Zhu, DB ;
Wong, M ;
Kwok, HS .
APPLIED PHYSICS LETTERS, 2002, 81 (04) :574-576
[8]   Aggregation-induced emission of cis,cis-1,2,3,4-tetraphenylbutadiene from restricted intramolecular rotation [J].
Chen, JW ;
Xu, B ;
Ouyang, XY ;
Tang, BZ ;
Cao, Y .
JOURNAL OF PHYSICAL CHEMISTRY A, 2004, 108 (37) :7522-7526
[9]   Synthesis, light emission, nanoaggregation, and restricted intramolecular rotation of 1,1-substituted 2,3,4,5-tetraphenylsiloles [J].
Chen, JW ;
Law, CCW ;
Lam, JWY ;
Dong, YP ;
Lo, SMF ;
Williams, ID ;
Zhu, DB ;
Tang, BZ .
CHEMISTRY OF MATERIALS, 2003, 15 (07) :1535-1546
[10]   Silole-containing polyacetylenes. Synthesis, thermal stability, light emission, nanodimensional aggregation, and restricted intramolecular rotation [J].
Chen, JW ;
Xie, ZL ;
Lam, JWY ;
Law, CCW ;
Tang, BZ .
MACROMOLECULES, 2003, 36 (04) :1108-1117