Population-Wide Generalizability of Genome-Wide Discovered Associations

被引:25
作者
Ioannidis, John P. A. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, GR-45110 Ioannina, Greece
[2] Fdn Res & Technol Hellas, Inst Biomed Res, Ioannina, Greece
[3] Tufts Med Ctr, Tufts Clin & Translat Sci Inst, Boston, MA USA
[4] Tufts Med Ctr, Ctr Genet Epidemiol & Modeling, Inst Clin Res & Hlth Policy Studies, Boston, MA USA
[5] Tufts Univ, Sch Med, Dept Med, Boston, MA 02111 USA
来源
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE | 2009年 / 101卷 / 19期
关键词
BREAST-CANCER RISK; HUMAN-DISEASES; LOCI; MULTIPLE;
D O I
10.1093/jnci/djp298
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1297 / 1299
页数:3
相关论文
共 18 条
[11]   GENOME-WIDE ASSOCIATION STUDIES Validating, augmenting and refining genome-wide association signals [J].
Ioannidis, John P. A. ;
Thomas, Gilles ;
Daly, Mark J. .
NATURE REVIEWS GENETICS, 2009, 10 (05) :318-329
[12]   'Racial' differences in genetic effects for complex diseases [J].
Ioannidis, JPA ;
Ntzani, EE ;
Trikalinos, TA .
NATURE GENETICS, 2004, 36 (12) :1312-1318
[13]   Genome-Wide Association Studies, Field Synopses, and the Development of the Knowledge Base on Genetic Variation and Human Diseases [J].
Khoury, Muin J. ;
Bertram, Lars ;
Boffetta, Paolo ;
Butterworth, Adam S. ;
Chanock, Stephen J. ;
Dolan, Siobhan M. ;
Fortier, Isabel ;
Garcia-Closas, Montserrat ;
Gwinn, Marta ;
Higgins, Julian P. T. ;
Janssens, A. Cecile J. W. ;
Ostell, James ;
Owen, Ryan P. ;
Pagon, Roberta A. ;
Rebbeck, Timothy R. ;
Rothman, Nathaniel ;
Bernstein, Jonine L. ;
Burton, Paul R. ;
Campbell, Harry ;
Chockalingam, Anand ;
Furberg, Helena ;
Little, Julian ;
O'Brien, Thomas R. ;
Seminara, Daniela ;
Vineis, Paolo ;
Winn, Deborah M. ;
Yu, Wei ;
Ioannidis, John P. A. .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2009, 170 (03) :269-279
[14]   Multiple novel prostate cancer predisposition loci confirmed by an international study:: The PRACTICAL consortium [J].
Kote-Jarai, Zsofia ;
Easton, Douglas F. ;
Stanford, Janet L. ;
Ostrander, Elaine A. ;
Schleutker, Johanna ;
Ingles, Sue A. ;
Schaid, Daniel ;
Thibodeau, Stephen ;
Doerk, Thilo ;
Neal, David ;
Cox, Angela ;
Maier, Christiane ;
Vogel, Walter ;
Guy, Michelle ;
Muir, Kenneth ;
Lophatananon, Artitaya ;
Kedda, Mary-Anne ;
Spurdle, Amanda ;
Steginga, Suzanne ;
John, Esther M. ;
Giles, Graham ;
Hopper, John ;
Chappuis, Pierre O. ;
Hutter, Pierre ;
Foulkes, William D. ;
Hamel, Nancy ;
Salinas, Claudia A. ;
Koopmeiners, Joseph S. ;
Karyadi, Danielle M. ;
Johanneson, Bo ;
Wahlfors, Tiina ;
Tammela, Teuvo L. ;
Stern, Mariana C. ;
Corral, Roman ;
McDonnell, Shannon K. ;
Schuermann, Peter ;
Meyer, Andreas ;
Kuefer, Rainer ;
Leongamornlert, Daniel A. ;
Tymrakiewicz, Malgorzata ;
Liu, Jo-fen ;
O'Mara, Tracy ;
Gardiner, R. A. ;
Aitken, Joanne ;
Joshi, Amit D. ;
Severi, Gianluca ;
English, Dallas R. ;
Southey, Melissa ;
Edwards, Stephen M. ;
Al Olama, Ali Amin .
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2008, 17 (08) :2052-2061
[15]   Opinion - Genes, environment and the value of prospective cohort studies [J].
Manolio, Teri A. ;
Bailey-Wilson, Joan E. ;
Collins, Francis S. .
NATURE REVIEWS GENETICS, 2006, 7 (10) :812-820
[16]   New insights into the aetiology of colorectal cancer from genome-wide association studies [J].
Tenesa, Albert ;
Dunlop, Malcolm G. .
NATURE REVIEWS GENETICS, 2009, 10 (06) :353-358
[17]   Quantifying and Correcting for the Winner's Curse in Genetic Association Studies [J].
Xiao, Rui ;
Boehnke, Michael .
GENETIC EPIDEMIOLOGY, 2009, 33 (05) :453-462
[18]   Replication of Prostate Cancer Risk Loci in a Japanese Case-Control Association Study [J].
Yamada, Hiroki ;
Penney, Kathryn L. ;
Takahashi, Hiroyuki ;
Katoh, Takahiko ;
Yamano, Yuko ;
Yamakado, Minoru ;
Kimura, Takahiro ;
Kuruma, Hidetoshi ;
Kamata, Yuko ;
Egawa, Shin ;
Freedman, Matthew L. .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2009, 101 (19) :1330-1336