A susceptible-infected epidemic model with voluntary vaccinations

被引:117
作者
Chen, Frederick H. [1 ]
机构
[1] Wake Forest Univ, Dept Econ, Winston Salem, NC 27109 USA
关键词
endemic equilibrium; reproductive number; dynamic programming; STD; voluntary vaccination; mass vaccination;
D O I
10.1007/s00285-006-0006-1
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
An susceptible-infected epidemic model with endogenous behavioral changes is presented to analyze the impact of a prophylactic vaccine on disease prevalence. It is shown that, with voluntary vaccination, whether an endemic equilibrium exists or not does not depend on vaccine efficacy or the distribution of agent-types. Although an endemic equilibrium is unique in the absence of a vaccine, the availability of a vaccine can lead to multiple endemic equilibria that differ in disease prevalence and vaccine coverage. Depending on the distribution of agent-types, the introduction of a vaccine or, if one is available, a subsidy for vaccination can increase disease prevalence by inducing more risky behavior.
引用
收藏
页码:253 / 272
页数:20
相关论文
共 24 条
[21]   Could disease-modifying HIV vaccines cause population-level perversity? [J].
Smith, RJ ;
Blower, SM .
LANCET INFECTIOUS DISEASES, 2004, 4 (10) :636-639
[22]   HIV vaccine development: Lessons from the past and promise for the future [J].
Spearman, P .
CURRENT HIV RESEARCH, 2003, 1 (01) :101-120
[23]   Population-level HIV declines and behavioral risk avoidance in Uganda [J].
Stoneburner, RL ;
Low-Beer, D .
SCIENCE, 2004, 304 (5671) :714-718
[24]  
UNAIDS, 2004, 4th global report