Pathology of in-stent restenosis

被引：177

作者：

Virmani, R ^{[1
]}

Farb, A ^{[1
]}

机构：

[1] Armed Forces Inst Pathol, Dept Cardiovasc Pathol, Washington, DC 20306 USA

来源：

CURRENT OPINION IN LIPIDOLOGY | 1999年 / 10卷 / 06期

关键词：

D O I：

10.1097/00041433-199912000-00004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The process of in-stent restenosis parallels wound healing responses. Stent deployment results in early thrombus deposition and acute inflammation, granulation tissue development, and ultimately smooth muscle cell proliferation and extracellular matrix synthesis. The severity of arterial injury during stent placement correlates with increased inflammation and late neointimal growth. These pathological findings provide useful targets for therapies aimed at reducing the incidence of in-Stent restenosis, Curr Opin Lipidol 10:499-506 (C) 1999 Lippincott Williams & Wilkins.

引用

页码：499 / 506

页数：8

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