dictyBase, the model organism database for Dictyostelium discoideum

被引:91
作者
Chisholm, Rex L. [1 ]
Gaudet, Pascale [1 ]
Just, Eric M. [1 ]
Pilcher, Karen E. [1 ]
Fey, Petra [1 ]
Merchant, Sohel N. [1 ]
Kibbe, Warren A. [1 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Ctr Med Genet, DictyBase, Chicago, IL 60611 USA
关键词
D O I
10.1093/nar/gkj090
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
dictyBase (http://dictybase.org) is the model organism database (MOD) for the social amoeba Dictyostelium discoideum. The unique biology and phylogenetic position of Dictyostelium offer a great opportunity to gain knowledge of processes not characterized in other organisms. The recent completion of the 34 MB genome sequence, together with the sizable scientific literature using Dictyostelium as a research organism, provided the necessary tools to create a well-annotated genome. dictyBase has lever-aged software developed by the Saccharomyces Genome Database and the Generic Model Organism Database project. This has reduced the time required to develop a full-featured MOD and greatly facilitated our ability to focus on annotation and providing new functionality. We hope that manual curation of the Dictyostelium genome will facilitate the annotation of other genomes.
引用
收藏
页码:D423 / D427
页数:5
相关论文
共 20 条
[11]   WormBase: a multi-species resource for nematode biology and genomics [J].
Harris, TW ;
Chen, NS ;
Cunningham, F ;
Tello-Ruiz, M ;
Antoshechkin, I ;
Bastiani, C ;
Bieri, T ;
Blasiar, D ;
Bradnam, K ;
Chan, J ;
Chen, CK ;
Chen, WJ ;
Davis, P ;
Kenny, E ;
Kishore, R ;
Lawson, D ;
Lee, R ;
Muller, HM ;
Nakamura, C ;
Ozersky, P ;
Petcherski, A ;
Rogers, A ;
Sabo, A ;
Schwarz, EM ;
Van Auken, K ;
Wang, QH ;
Durbin, R ;
Spieth, J ;
Sternberg, PW ;
Stein, LD .
NUCLEIC ACIDS RESEARCH, 2004, 32 :D411-D417
[12]   The signal to move:: D-discoideum go orienteering [J].
Kimmel, AR ;
Parent, CA .
SCIENCE, 2003, 300 (5625) :1525-1527
[13]   dictyBase:: a new Dictyostelium discoideum genome database [J].
Kreppel, L ;
Fey, P ;
Gaudet, P ;
Just, E ;
Kibbe, WA ;
Chisholm, RL ;
Kimmel, AR .
NUCLEIC ACIDS RESEARCH, 2004, 32 :D332-D333
[14]   Molecular basis for resistance to the anticancer drug cisplatin in Dictyostelium [J].
Li, GC ;
Alexander, H ;
Schneider, N ;
Alexander, S .
MICROBIOLOGY-SGM, 2000, 146 :2219-2227
[15]   Dictyostelium discoideum strains lacking the RtoA protein are defective for maturation of the Legionella pneumophila replication vacuole [J].
Li, ZR ;
Solomon, JM ;
Isberg, RR .
CELLULAR MICROBIOLOGY, 2005, 7 (03) :431-442
[16]   Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner [J].
Min, JX ;
Van Veldhoven, PP ;
Zhang, L ;
Hanigan, MH ;
Alexander, H ;
Alexander, S .
MOLECULAR CANCER RESEARCH, 2005, 3 (05) :287-296
[17]   Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin [J].
Min, JX ;
Traynor, D ;
Stegner, AL ;
Zhang, L ;
Hanigan, MH ;
Alexander, H ;
Alexander, S .
EUKARYOTIC CELL, 2005, 4 (01) :178-189
[18]   Making all the right moves:: chemotaxis in neutrophils and Dictyostelium [J].
Parent, CA .
CURRENT OPINION IN CELL BIOLOGY, 2004, 16 (01) :4-13
[19]   Chemotaxis: Signalling the way forward [J].
Van Haastert, PJM ;
Devreotes, PN .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2004, 5 (08) :626-634
[20]  
Weeks G. G. P, 2005, DICTYOSTELIUM GENOMI, P173