Won't you be my neighbor? Local induction of arteriogenesis

被引：38

作者：

D'Amore, PA ^{[1
]}

Ng, YS

机构：

[1] Schepens Eye Res Inst, Boston, MA 02114 USA

[2] Harvard Univ, Sch Med, Boston, MA 02114 USA

来源：

CELL | 2002年 / 110卷 / 03期

关键词：

D O I：

10.1016/S0092-8674(02)00869-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two recent papers in Cell and Developmental Cell provide evidence that VEGF directs arterial differentiation. Evidence that sensory nerves direct arteriogenesis (Mukouyama et al., 2002) and that the membrane-spanning Notch signaling system is downstream of VEGF (Lawson et al., 2002) emphasize the paracrine regulation of vessel formation.

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收藏

页码：289 / 292

页数：4

相关论文

共 20 条

[11]

Ng YS, 2001, DEV DYNAM, V220, P112, DOI 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1093>3.0.CO

[12]

2-D

[13] Sonic hedgehog regulates branching morphogenesis in the mammalian lung [J].

Pepicelli, CV ;

Lewis, PM ;

McMahon, AP .

CURRENT BIOLOGY, 1998, 8 (19) :1083-1086

[14] The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors [J].

Pola, R ;

Ling, LE ;

Silver, M ;

Corbley, MJ ;

Kearney, M ;

Pepinsky, RB ;

Shapiro, R ;

Taylor, FR ;

Baker, DP ;

Asahara, T ;

Isner, JM .

NATURE MEDICINE, 2001, 7 (06) :706-711

[15] Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells [J].

Rowitch, DH ;

St-Jacques, B ;

Lee, SMK ;

Flax, JD ;

Snyder, EY ;

McMahon, AP .

JOURNAL OF NEUROSCIENCE, 1999, 19 (20) :8954-8965

[16] Vascular developmental biology: getting nervous [J].

Shima, DT ;

Mailhos, C .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2000, 10 (05) :536-542

[17] Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor [J].

Soker, S ;

Takashima, S ;

Miao, HQ ;

Neufeld, G ;

Klagsbrun, M .

CELL, 1998, 92 (06) :735-745

[18] Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms [J].

Stalmans, I ;

Ng, YS ;

Rohan, R ;

Fruttiger, M ;

Bouché, A ;

Yuce, A ;

Fujisawa, H ;

Hermans, B ;

Shani, M ;

Jansen, S ;

Hicklin, D ;

Anderson, DJ ;

Gardiner, T ;

Hammes, HP ;

Moons, L ;

Dewerchin, M ;

Collen, D ;

Carmeliet, P ;

D'Amore, PA .

JOURNAL OF CLINICAL INVESTIGATION, 2002, 109 (03) :327-336

[19] DEVELOPMENT OF RETINAL VASCULATURE IS MEDIATED BY HYPOXIA-INDUCED VASCULAR ENDOTHELIAL GROWTH-FACTOR (VEGF) EXPRESSION BY NEUROGLIA [J].

STONE, J ;

ITIN, A ;

ALON, T ;

PEER, J ;

GNESSIN, H ;

CHANLING, T ;

KESHET, E .

JOURNAL OF NEUROSCIENCE, 1995, 15 (07) :4738-4747

[20] Gridlock signalling pathway fashions the first embryonic artery [J].

Zhong, TP ;

Childs, S ;

Leu, JP ;

Fishman, MC .

NATURE, 2001, 414 (6860) :216-220