Cytotoxic and antioxidative sesquiterpenoids from Heterotheca inuloides

被引：142

作者：

Kubo, I

Chaudhuri, SK

Kubo, Y

Sanchez, Y

Ogura, T

Saito, T

Ishikawa, H

Haraguchi, H

机构：

[1] UNIV AUTONOMA GUADALAJARA, DEPT QUIM, GUADALAJARA, JALISCO, MEXICO

[2] FUKUYAMA UNIV, FAC ENGN, HIROSHIMA 72902, JAPAN

来源：

PLANTA MEDICA | 1996年 / 62卷 / 05期

关键词：

Heterotheca inuloides; Asteraceae; cytotoxic activity; antioxidant activity; sesquiterpenoids; 7-hydroxy-3,4-dihydrocadalin; 7-hydroxycadalin;

D O I：

10.1055/s-2006-957932

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four sesquiterpenoids, beta-caryophyllene, beta-caryophyllene 4,5 alpha-oxide, 7-hydroxy-3,4-dihydrocadalin, and 7-hydroxycadalin, isolated from the dried flower of Heterotheca inuloides Cass. (Asteraceae), have been found to exhibit cytotoxic activity against several solid tumor cell lines. Among them, 7-hydroxy-3,4-dihydrocadalin and 7-hydroxycadalin have also been found to inhibit autoxidative and microsomal lipid peroxidation.

引用

页码：427 / 430

页数：4

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