Cyclopropanation of alkenes mediated by novel chiral Fischer carbene complexes

被引：8

作者：

Barluenga, J ^{[1
]}

Muñiz, K ^{[1
]}

Ballesteros, A ^{[1
]}

Martínez, S ^{[1
]}

Tomás, M ^{[1
]}

机构：

[1] Univ Oviedo, Inst Univ Quim Organomet E Moles, Julian Claveria 8, E-33006 Oviedo, Spain

来源：

ARKIVOC | 2002年

关键词：

cyclopropanation; alkenes; chiral Fischer carbene complexes; group; 6; diastereoselective; enantioselective;

D O I：

10.3998/ark.5550190.0003.513

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cyclopropanation reaction using chiral-at-metal Fischer carbene complexes is examined. Racemic molybdenum and chromium carbene complexes fac- and mer-1 and mer-2, respectively, undergo cycloaddition to acrylonitrile, methyl acrylate and 1-hexene to give cylopropanes 3 and 4 with trans/cis ratio up to 4.7:1. The cyclopropanation of acrylonitrile with the enantiopure carbene complex (+)-mer-1 resulted in a modest asymmetric induction of 2: 1 for the transisomer 3a.

引用

页码：110 / 119

页数：10

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