Cost-effective flow injection spectrophotometric assay of iron content in pharmaceutical preparations using salicylate reagent

被引：14

作者：

Udnan, Y

Jakmunee, J

Jayasavati, S

Christian, GD

Synovec, RE

Grudpan, K ^{[1
]}

机构：

[1] Chiang Mai Univ, Dept Chem, Fac Sci, Chiang Mai 50200, Thailand

[2] Chiang Mai Univ, Inst Sci & Technol Res & Dev, Chiang Mai 50200, Thailand

[3] Chiang Mai Univ, Fac Med, Dept Radiol, Chiang Mai 50200, Thailand

[4] Univ Washington, Dept Chem, Seattle, WA 98195 USA

来源：

TALANTA | 2004年 / 64卷 / 05期

关键词：

drugs; flow injection; iron; salicylate; aspirin;

D O I：

10.1016/j.talanta.2004.03.067

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A new flow injection procedure for an assay of Fe(III) by using salicylate obtained from antipyretic powder, which is a cheap and easily available reagent, is proposed. A red complex was continuously monitored by a laboratory-made green LED colorimeter. A linear calibration was obtained in the range of 1-20 mg Fe l(-1) with a detection limit of 0.5 mg Fe l(-1) and R.S.D.s of 1.4-5.4% (n = 3, for 1-20 mg Fe l(-1)). The new procedure was applied to assay iron contents in pharmaceutical preparations. The results were in good agreement with those of the USP standard method. (C) 2004 Published by Elsevier B.V.

引用

页码：1237 / 1240

页数：4

共 11 条

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