A compiled and systematic reference map of nucleosome positions across the Saccharomyces cerevisiae genome

被引：180

作者：

Jiang, Cizhong ^{[1
]}

Pugh, B. Franklin ^{[1
]}

机构：

[1] Penn State Univ, Ctr Eukaryot Gene Regulat, N Frear Lab 456, Dept Biochem & Mol Biol, University Pk, PA 16802 USA

来源：

GENOME BIOLOGY | 2009年 / 10卷 / 10期

关键词：

HIGH-RESOLUTION; DNA; TRANSCRIPTION; YEAST; ORGANIZATION; POLY(DA-DT); PARTICLE; CORE;

D O I：

10.1186/gb-2009-10-10-r109

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Nucleosomes have position-specific functions in controlling gene expression. A complete systematic genome-wide reference map of absolute and relative nucleosome positions is needed to minimize potential confusion when referring to the function of individual nucleosomes (or nucleosome-free regions) across datasets. We compiled six high-resolution genome-wide maps of Saccharomyces cerevisiae nucleosome positions from multiple labs and detection platforms, and report new insights. Data downloads, reference position assignment software, queries, and a visualization browser are available online http://atlas.bx.psu.edu/.

引用

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