The final cut:: how ERAPI trims MHC ligands to size

被引:20
作者
Falk, K [1 ]
Rötzschke, O [1 ]
机构
[1] Max Delbruck Ctr Mol Med, D-13125 Berlin, Germany
关键词
D O I
10.1038/ni1202-1121
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 [免疫学];
摘要
Proteolytic cleavage generates the peptide repertoire displayed by MHC class I. Now, an interferon-gamma-inducible aminopeptidase in the endoplasmic reticulum has been identified as the final player in this complex process.
引用
收藏
页码:1121 / 1122
页数:2
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