Cocarcinogenic effects of alcohol in hepatocarcinogenesis

被引：97

作者：

Stickel, F

Schuppan, D

Hahn, EG

Seitz, HK

机构：

[1] Univ Erlangen Nurnberg, Dept Med 1, Div Hepatol, D-91054 Erlangen, Germany

[2] Salem Med Ctr, Lab Alcohol Res Liver Dis & Nutr, Heidelberg, Germany

[3] Salem Med Ctr, Dept Med, Heidelberg, Germany

来源：

GUT | 2002年 / 51卷 / 01期

关键词：

D O I：

10.1136/gut.51.1.132

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Alcohol is a major aetiological factor in hepatocarcinogenesis but our understanding of its importance as a modulating factor is just beginning to emerge. In the present review, a number of possible cofactors and mechanisms are discussed by which alcohol may enhance the development of hepatoma. These include dietary or environmental carcinogens ingested along with alcoholic beverages, alcoholic cirrhosis as a precancerous condition, and the effects of alcohol metabolism.

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页码：132 / 139

页数：8

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