Analysis of human and swine hepatitis E virus (HEV) isolates of genotype 3 in Japan that are only 81-83% similar to reported HEV isolates of the same genotype over the entire genome

被引：28

作者：

Inoue, Jun

Takahashi, Masaharu

Ito, Keiichi

Shimosegawa, Tooru

Okamoto, Hiroaki ^{[1
]}

机构：

[1] Jichi Med Sch, Dept Infect & Immun, Div Virol, Tochigi 3290498, Japan

[2] Tohoku Univ, Grad Sch Med, Div Gastroenterol, Sendai, Miyagi 9808574, Japan

[3] Mie Univ, Sch Med, Dept Internal Med 1, Tsu, Mie 5148507, Japan

来源：

JOURNAL OF GENERAL VIROLOGY | 2006年 / 87卷

关键词：

D O I：

10.1099/vir.0.81912-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Full-length sequences were determined for a human hepatitis E virus (HEV) isolate (HE-JA04-1911) and two swine HEV isolates (swJ8-6 and swJ12-4) that belong to one of three clusters within genotype 3 in Japan and are close to Spanish isolates according to their partial sequences. The three HEV isolates were 89.7-92.9% identical to each other, but only 80.7-83.0% similar to 21 HEV strains of the same genotype isolated in Canada, Kyrgyzstan, the USA and Japan over their entire genome. On comparison with HEV isolates whose partial sequence is known, the HE-JA04-1911, swJ8-5 and swJ12-4 isolates segregated into a phylogenetic cluster consisting of human and swine HEV isolates in Japan and the UK, with identities of 89.8-100% and 87.9-92.4%, respectively. Genotype 3 HEV isolates were found to be markedly heterogeneous. The UK-isolate-like HEV strains in Japan may have originated from the UK via the importation of pigs since 1900.

引用

页码：2363 / 2369

页数：7

共 37 条

[1] Human and porcine hepatitis E virus strains, United Kingdom [J].

Banks, M ;

Bendall, R ;

Grierson, S ;

Heath, G ;

Mitchell, J ;

Dalton, H .

EMERGING INFECTIOUS DISEASES, 2004, 10 (05) :953-955

[2]

Emerson S. U., 2004, VIRUS TAXONOMY, P851

[3]

FELSENSTEIN J, 1985, EVOLUTION, V39, P783, DOI 10.1111/j.1558-5646.1985.tb00420.x

[4] Hepatitis E virus - an update [J].

Harrison, TJ .

LIVER, 1999, 19 (03) :171-176

[5] Identity of a novel swine hepatitis E virus in Taiwan forming a monophyletic group with Taiwan isolates of human hepatitis E virus [J].

Hsieh, SY ;

Meng, XJ ;

Wu, YH ;

Liu, ST ;

Tam, AW ;

Lin, DY ;

Liaw, YF .

JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (12) :3828-3834

[6] Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV [J].

Huang, FF ;

Sun, ZF ;

Emerson, SU ;

Purcell, RH ;

Shivaprasad, HL ;

Pierson, FW ;

Toth, TE ;

Meng, XJ .

JOURNAL OF GENERAL VIROLOGY, 2004, 85 :1609-1618

[7] Non-travel-associated Hepatitis C in England and Wales: Demographic, clinical, and molecular epidemiological characteristics [J].

Ijaz, S ;

Arnold, E ;

Banks, M ;

Bendall, RP ;

Cramp, ME ;

Cunningham, R ;

Dalton, HR ;

Harrison, TJ ;

Hill, SF ;

MacFarlane, L ;

Meigh, RE ;

Shafi, S ;

Sheppard, MJ ;

Smithson, J ;

Wilson, MP ;

Teo, CG .

JOURNAL OF INFECTIOUS DISEASES, 2005, 192 (07) :1166-1172

[8] A broadly reactive one-step real-time RT-PCR assay for rapid and sensitive detection of hepatitis E virus [J].

Jothikumar, N ;

Cromeans, TL ;

Robertson, BH ;

Meng, XJ ;

Hill, VR .

JOURNAL OF VIROLOGICAL METHODS, 2006, 131 (01) :65-71

[9] Hepatitis E virus transmission from wild boar meat [J].

Li, TC ;

Chijiwa, K ;

Sera, N ;

Ishibashi, T ;

Etoh, Y ;

Shinohara, Y ;

Kurata, Y ;

Ishida, M ;

Sakamoto, S ;

Takeda, N ;

Miyamura, T .

EMERGING INFECTIOUS DISEASES, 2005, 11 (12) :1958-1960

[10] Complete sequence of a kyrgyzstan swine hepatitis E virus (HEV) isolated from a piglet thought to be experimentally infected with human HEV [J].

Lu, L ;

Drobeniuc, J ;

Kobylnikov, N ;

Usmanov, RK ;

Robertson, BH ;

Favorov, MO ;

Margolis, HS .

JOURNAL OF MEDICAL VIROLOGY, 2004, 74 (04) :556-562

← 1 2 3 4 →