Insects: True Pioneers in Anti-Infective Therapy and What We Can Learn from Them

被引：41

作者：

Bode, Helge B. ^{[1
]}

机构：

[1] Goethe Univ Frankfurt, Inst Mol Biowissensch, D-60438 Frankfurt, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 35期

关键词：

anti-infectives; bacteria; drug discovery; insects; symbiosis; NATURAL-PRODUCTS; BACTERIA; ANTS; METABOLITES; CHEMISTRY; PROTECT; GARDEN;

D O I：

10.1002/anie.200902152

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Candicidin D is a potent natural product that was recently re-isolated from bacterial insect symbionts. Some insects cultivate the producing bacteria in specialized organs in order to fight pathogens. Besides the identification of new natural products for human use, these findings have also implications for our understanding of resistance development and drug discovery strategies in general. © 2009 Wiley-VCH Verlag GmbH & Co. KCaA.

引用

页码：6394 / 6396

页数：3

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