Key factors in the rising cost of new drug discovery and development

被引：313

作者：

Dickson, M ^{[1
]}

Gagnon, JP

机构：

[1] Univ S Carolina, Coll Pharm, Columbia, SC 29208 USA

[2] Aventis Pharmaceut, Bridgewater, NJ 08807 USA

来源：

NATURE REVIEWS DRUG DISCOVERY | 2004年 / 3卷 / 05期

关键词：

D O I：

10.1038/nrd1382

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The public desire for new therapies, their increasing cost and the increased role of government as a payer for innovative new drugs all converge on the issue of the rapidly rising cost of new drug development-now thought to be greater than US $800 million-and highlight the necessity for an efficient use of resources. With this in mind, here we review studies on the cost of developing new drugs and consider how this cost has, and could be, affected by the changing environment for pharmaceutical research and development.

引用

页码：417 / 429

页数：13

共 52 条

[11]

*ERNST YOUNG, 2002, PHARM IND R D COSTS

[12] Increasing use of new prescription drugs:: A case study -: Recent experience with new antidepressants suggests that without move efforts to identify and promote effective use, biomedical innovation may fall short of its promise. [J].