Plasmodium: Drug discovery and development - An industrial perspective

被引:31
作者
Ridley, RG
机构
[1] Pharma Division, F. Hoffmann-La Roche
关键词
D O I
10.1006/expr.1997.4230
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
[No abstract available]
引用
收藏
页码:293 / 304
页数:12
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共 52 条
  • [31] New targets for antimalarial drug discovery
    Olliaro, P
    Wirth, D
    [J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1997, 49 : 29 - 33
  • [32] THE PLASMODIUM DIGESTIVE VACUOLE - METABOLIC HEADQUARTERS AND CHOICE DRUG TARGET
    OLLIARO, PL
    GOLDBERG, DE
    [J]. PARASITOLOGY TODAY, 1995, 11 (08): : 294 - 297
  • [33] Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues
    ONeill, PM
    Willock, DJ
    Hawley, SR
    Bray, PG
    Storr, RC
    Ward, SA
    Park, BK
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (04) : 437 - 448
  • [34] Depolymerization of malarial hemozoin: A novel reaction initiated by blood schizontocidal antimalarials
    Pandey, AV
    Tekwani, BL
    [J]. FEBS LETTERS, 1997, 402 (2-3) : 236 - 240
  • [35] THE CHEMOTHERAPY OF RODENT MALARIA .50. THE ACTIVITIES OF SOME SYNTHETIC 1,2,4-TRIOXANES AGAINST CHLOROQUINE-SENSITIVE AND CHLOROQUINE-RESISTANT PARASITES .3. OBSERVATIONS ON FENOZAN-50F, A DIFLUORINATED 3,3'-SPIROCYCLOPENTANE 1,2,4-TRIOXANE
    PETERS, W
    ROBINSON, BL
    TOVEY, G
    ROSSIER, JC
    JEFFORD, CW
    [J]. ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 1993, 87 (02): : 111 - 123
  • [36] Antimalarial endoperoxides that are potent and easily synthesized
    Posner, GH
    [J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1997, 49 : 55 - 57
  • [37] Arteflene compared with mefloquine for treating Plasmodium falciparum malaria in children
    Radloff, PD
    Philipps, J
    Nkeyi, M
    Sturchler, D
    Mittelholzer, ML
    Kremsner, PG
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1996, 55 (03) : 259 - 262
  • [38] 4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum
    Ridley, RG
    Hofheinz, W
    Matile, H
    Jaquet, C
    Dorn, A
    Masciadri, R
    Jolidon, S
    Richter, WF
    Guenzi, A
    Girometta, MA
    Urwyler, H
    Huber, W
    Thaithong, S
    Peters, W
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (08) : 1846 - 1854
  • [39] Haemoglobin degradation and haem polymerization as antimalarial drug targets
    Ridley, RG
    [J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1997, 49 : 43 - 48
  • [40] Ridley RG, 1997, ANN TROP MED PARASIT, V91, P559, DOI 10.1080/00034989760932