Detection of artifacts and peptide modifications in liquid chromatography/mass spectrometry data using two-dimensional signal intensity map data visualization

被引:18
作者
Berg, M
Parbel, A
Pettersen, H
Fenyö, D
Björkesten, L
机构
[1] GE Healthcare, D-80807 Munich, Germany
[2] GE Healthcare, Uppsala, Sweden
关键词
D O I
10.1002/rcm.2476
中图分类号
Q5 [生物化学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
We demonstrate how visualization of liquid chromatography/mass spectrometry data as a two-dimensional signal intensity map can be used to assess the overall quality of the data, for the identification of polymer contaminants and artifacts, as well as for the confirmation of post-translational modifications. Copyright (c) 2006 John Wiley & Sons, Ltd.
引用
收藏
页码:1558 / 1562
页数:5
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