Postsynthetic modification of an amino-tagged MOF using peptide coupling reagents: a comparative study

被引：66

作者：

Hintz, Henrik

Wuttke, Stefan ^{[1
]}

机构：

[1] Univ Munich LMU, Dept Chem, D-81377 Munich, Germany

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 78期

关键词：

METAL-ORGANIC FRAMEWORK; FUNCTIONALIZATION;

D O I：

10.1039/c4cc02650k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The suitability of four peptide coupling reagents for postsynthetic modification (PSM) of amino-tagged metal-organic frameworks (MOFs) with carboxylic acids was investigated. Mild reaction conditions at room temperature allow effective covalent attachment of drugs and biomolecules inside the pores of MOFs with moderate chemical stability.

引用

收藏

页码：11472 / 11475

页数：4

相关论文

共 24 条

[1] N,N'-CARBONYLDIIMIDAZOLE, A NEW REAGENT FOR PEPTIDE SYNTHESIS [J].

ANDERSON, GW ;

PAUL, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1958, 80 (16) :4423-4423

[2] Amino acid functionalized metal-organic frameworks by a soft coupling-deprotection sequence [J].

Canivet, Jerome ;

Aguado, Sonia ;

Bergeret, Gerard ;

Farrusseng, David .

CHEMICAL COMMUNICATIONS, 2011, 47 (42) :11650-11652

[3] Postsynthetic Methods for the Functionalization of Metal-Organic Frameworks [J].

Cohen, Seth M. .

CHEMICAL REVIEWS, 2012, 112 (02) :970-1000

[4] Modifying MOFs: new chemistry, new materials [J].

Cohen, Seth M. .

CHEMICAL SCIENCE, 2010, 1 (01) :32-36

[5] Engineering Metal Organic Frameworks for Heterogeneous Catalysis [J].

Corma, A. ;

Garcia, H. ;

Llabres i Xamena, F. X. L. I. .

CHEMICAL REVIEWS, 2010, 110 (08) :4606-4655

[6] PYBOP - A NEW PEPTIDE COUPLING REAGENT DEVOID OF TOXIC BY-PRODUCT [J].

COSTE, J ;

LENGUYEN, D ;

CASTRO, B .

TETRAHEDRON LETTERS, 1990, 31 (02) :205-208

[7]

DOURTOGLOU V, 1978, TETRAHEDRON LETT, P1269

[8] Systematic design of pore size and functionality in isoreticular MOFs and their application in methane storage [J].

Eddaoudi, M ;

Kim, J ;

Rosi, N ;

Vodak, D ;

Wachter, J ;

O'Keeffe, M ;

Yaghi, OM .

SCIENCE, 2002, 295 (5554) :469-472

[9] Metal-Organic Framework Materials with Ultrahigh Surface Areas: Is the Sky the Limit? [J].

Farha, Omar K. ;

Eryazici, Ibrahim ;

Jeong, Nak Cheon ;

Hauser, Brad G. ;

Wilmer, Christopher E. ;

Sarjeant, Amy A. ;

Snurr, Randall Q. ;

Nguyen, SonBinh T. ;

Yazaydin, A. Oezguer ;

Hupp, Joseph T. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (36) :15016-15021

[10] Hybrid porous solids:: past, present, future [J].

Ferey, Gerard .

CHEMICAL SOCIETY REVIEWS, 2008, 37 (01) :191-214