Postsynthetic modification of an amino-tagged MOF using peptide coupling reagents: a comparative study

被引:66
作者
Hintz, Henrik
Wuttke, Stefan [1 ]
机构
[1] Univ Munich LMU, Dept Chem, D-81377 Munich, Germany
关键词
METAL-ORGANIC FRAMEWORK; FUNCTIONALIZATION;
D O I
10.1039/c4cc02650k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The suitability of four peptide coupling reagents for postsynthetic modification (PSM) of amino-tagged metal-organic frameworks (MOFs) with carboxylic acids was investigated. Mild reaction conditions at room temperature allow effective covalent attachment of drugs and biomolecules inside the pores of MOFs with moderate chemical stability.
引用
收藏
页码:11472 / 11475
页数:4
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