High-throughput carbohydrate microarray analysis of 24 lectins

被引：131

作者：

Manimala, Joseph C. ^{[1
]}

Roach, Timothy A. ^{[1
]}

Li, Zhitao ^{[1
]}

Gildersleeve, Jeffrey C. ^{[1
]}

机构：

[1] NCI, Ctr Canc Res, Med Chem Lab, Ft Detrick, MD 21702 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 22期

关键词：

carbohydrates; glycoconjugates; glycosides; lectins; microarrays;

D O I：

10.1002/anie.200600591

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Hip hip array: Lectins are involved in a wide range of biological processes and are used frequently as tools for basic and applied research. Through the use of a carbohydrate microarray, high-throughput analysis of lectin specificity was carried out on 24 different lectins. Many of the carbohydrate ligands identified for the lectins were unexpected based on previous information. (Figure Presented). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3607 / 3610

页数：4

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