Preparation of primary amine-modified gold nanoparticles and their transfection ability into cultivated cells

被引：186

作者：

Niidome, T

Nakashima, K

Takahashi, H

Niidome, Y

机构：

[1] Nagasaki Univ, Grad Sch Sci & Technol, Dept Mat Sci, Nagasaki 8528521, Japan

[2] Nagasaki Univ, Fac Engn, Dept Appl Chem, Nagasaki 8528521, Japan

[3] Kyushu Univ, Grad Sch Engn, Dept Appl Chem, Fukuoka 8128581, Japan

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 17期

关键词：

D O I：

10.1039/b406189f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cationic gold nanoparticles, prepared by reducing HAuCl4 with NaBH4 in the presence of 2-aminoethanethiol, formed a complex with plasmid DNA, and could be transfected into cultivated cells.

引用

页码：1978 / 1979

页数：2

共 7 条

[1] Non-viral gene delivery systems [J].

Davis, ME .

CURRENT OPINION IN BIOTECHNOLOGY, 2002, 13 (02) :128-131

[2] POLYAMIDOAMINE CASCADE POLYMERS MEDIATE EFFICIENT TRANSFECTION OF CELLS IN CULTURE [J].

HAENSLER, J ;

SZOKA, FC .

BIOCONJUGATE CHEMISTRY, 1993, 4 (05) :372-379

[3] A nonviral DNA delivery system based on surface modified silica-nanoparticles can efficiently transfect cells in vitro [J].

Kneuer, C ;

Sameti, M ;

Bakowsky, U ;

Schiestel, T ;

Schirra, H ;

Schmidt, H ;

Lehr, CM .

BIOCONJUGATE CHEMISTRY, 2000, 11 (06) :926-932

[4] Gene therapy progress and prospects: Nonviral vectors [J].

Niidome, T ;

Huang, L .

GENE THERAPY, 2002, 9 (24) :1647-1652

[5] In vitro gene Transfection using dendritic poly(L-lysine) [J].

Ohsaki, M ;

Okuda, T ;

Wada, A ;

Hirayama, T ;

Niidome, T ;

Aoyagi, H .

BIOCONJUGATE CHEMISTRY, 2002, 13 (03) :510-517

[6] Gold nanoparticle-mediated Transfection of mammalian cells [J].

Sandhu, KK ;

McIntosh, CM ;

Simard, JM ;

Smith, SW ;

Rotello, VM .

BIOCONJUGATE CHEMISTRY, 2002, 13 (01) :3-6

[7] Metal coating of DNA molecules by cationic, metastable gold nanoparticles [J].

Yonezawa, T ;

Onoue, SY ;

Kimizuka, N .

CHEMISTRY LETTERS, 2002, (12) :1172-1173

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