Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion

被引:552
作者
Kriegstein, Arnold [1 ]
Noctor, Stephen [1 ]
Martinez-Cerdeno, Veronica [1 ]
机构
[1] Univ Calif San Francisco, Inst Stem Cell & Tissue Biol, San Francisco, CA 94143 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1038/nrn2008
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The dramatic evolutionary expansion of the cerebral cortex of Homo sapiens underlies our unique higher cortical functions, and therefore bears on the ultimate issue of what makes us human. Recent insights into developmental events during early proliferative stages of cortical development indicate how neural stem and progenitor cells might interact to produce cortical expansion during development, and could shed light on evolutionary changes in cortical structure.
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页码:883 / 890
页数:9
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