Synthesis of selenium- and tellurium-containing nucleosides derived from uridine

被引：35

作者：

Braga, Antonio L. ^{[1
]}

Severo Filho, Wolmar A. ^{[1
,2
]}

Schwab, Ricardo S. ^{[1
]}

Rodrigues, Oscar E. D. ^{[1
]}

Dornelles, Luciano ^{[2
]}

Braga, Hugo C. ^{[3
]}

Ludtke, Diogo S. ^{[3
]}

机构：

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

[2] Univ Santa Cruz do Sul, Dept Quim & Fis, BR-96815900 Santa Cruz Do Sul, RS, Brazil

[3] Univ Sao Paulo, Fac Ciencias Farmaceut, BR-05508900 Sao Paulo, Brazil

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 25期

基金：

巴西圣保罗研究基金会;

关键词：

Nucleosides; Uridine; Selenium; Tellurium; Diselenide; Telluride; Organochalcogen; STEREOSELECTIVE-SYNTHESIS; STRAIGHTFORWARD SYNTHESIS; CONTAINING OXAZOLINES; ACID-DERIVATIVES; OLIGONUCLEOTIDES; ORGANOSELENIUM; DERIVATIZATION; SELENOCYSTEINE; CHEMISTRY; CATALYSTS;

D O I：

10.1016/j.tetlet.2009.03.164

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

The synthesis of selenium- and tellurium-containing nucleosides, derived from uridine is described herein. These compounds were prepared in a concise and short synthetic route in good yields, by nucleophilic substitution of a tosylate group by organoselenium nucleophiles. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：3005 / 3007

页数：3

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