Characterization of the diversity and the transferrin-binding domain of gonococcal transferrin-binding protein 2

被引:42
作者
Cornelissen, CN [1 ]
Anderson, JE [1 ]
Sparling, PF [1 ]
机构
[1] UNIV N CAROLINA, DEPT MICROBIOL & IMMUNOL, SCH MED, CHAPEL HILL, NC 27599 USA
关键词
D O I
10.1128/IAI.65.2.822-828.1997
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The molecular weight heterogeneities of Tbp1 and Tbp2 among a panel of 45 gonococcal isolates were assessed. The tbpB genes from four of these strains were sequenced to characterize the Thp2 sequence diversity among gonococci. By expressing truncated versions of gonococcal Tbp3, we delimited the extent of Tbp2 necessary for transferrin binding in a Western blot.
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页码:822 / 828
页数:7
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