Tetraarylporphyrin as a selective molecular cap for non-Watson-Crick guanine-adenine base-pair sequences

被引：28

作者：

Balaz, Milan ^{[1
]}

Li, Benjamin C. ^{[1
]}

Jockusch, Steffen ^{[1
]}

Ellestad, George A. ^{[1
]}

Berova, Nina ^{[1
]}

机构：

[1] Columbia Univ, Dept Chem, New York, NY 10027 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 21期

关键词：

circular dichroism; DNA structures; fluorescence; mismatched base pairs; porphyrinoids;

D O I：

10.1002/anie.200504431

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Well protected: Porphyrins act as a molecular cap (see picture) to selectively stabilize a non-self-complementary non-Watson-Crick DNA structure through additional hydrophobic interactions. At the same time, these porphyrins serve as an efficient internal sensor of the newly formed secondary structure. (Chemical Equation Presented). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3530 / 3533

页数：4

共 58 条

[31] Binding mode of cationic monomer and dimer porphyrin with native and synthetic polynucleotides studied by polarized light spectroscopy [J].